DAZAP1

Across TCGA cell cohorts, DAZAP1 mutation is significantly associated with the RNA expression of many other genes, with 605 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DAZAP1-associated genes across cancer lineages are SOX10, MUC5B, and FBXL8. Each is linked with DAZAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAZAP1-to-partner and partner-to-DAZAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOX10 grouped by DAZAP1-low versus DAZAP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAZAP1→partner) and Y-score (partner→DAZAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SOX10 →	+0.157	+3.314	<.001	.005	3	2
LARGE_INTESTINE	MUC5B →	+2.238	+3.364	<.001	.002	3	2
LARGE_INTESTINE	FBXL8 →	+0.965	+3.364	.002	.002	3	2
LARGE_INTESTINE	TMEM50B →	+0.600	+3.169	.001	.006	3	2
LARGE_INTESTINE	FRA10AC1 →	+0.713	+3.364	<.001	.002	3	2
LARGE_INTESTINE	FCSK →	+0.841	+3.364	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

SOX10 by DAZAP1 expression — LARGE_INTESTINE

Explore this box plot interactively →