Across TCGA cell cohorts, DAZ3 RNA expression is significantly associated with the mutation status of many other genes, with 65 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DAZ3-associated genes across cancer lineages are OR5AU1, PCDHB4, and SCN7A. Each is linked with DAZ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAZ3-to-partner and partner-to-DAZ3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAZ3→partner) and Y-score (partner→DAZ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR5AU1 →	+5.539	+0.012	.003	<.001	3	2
CNS	PCDHB4 →	+3.832	+1.003	.005	.002	3	2
BLOOD_Myeloma	SCN7A →	+4.807	+1.563	.006	<.001	3	1
BLOOD_Myeloma	PPARGC1B →	+4.807	+1.563	.006	<.001	3	1
BLOOD_Myeloma	GPHN →	+4.807	+1.563	.006	<.001	3	1
BLOOD_Myeloma	GPR4 →	+4.807	+1.563	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

DAZ3 survival (RNA) · tumor vs normal (RNA) · all DAZ3 data types