DAW1

Across TCGA patient cohorts, DAW1 mutation is significantly associated with the RNA expression of many other genes, with 4,855 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAW1-associated genes across cancer lineages are MIR6803, HMX3, and ERP27. Each is linked with DAW1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAW1-to-partner and partner-to-DAW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by DAW1-low versus DAW1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAW1→partner) and Y-score (partner→DAW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.126	+4.256	<.001	<.001	3	3
UCEC	HMX3 →	+0.394	+1.818	.004	<.001	3	3
UCEC	ERP27 →	-1.381	-2.367	<.001	<.001	3	2
SKCM	GALNT6 →	-0.773	-1.906	.004	.005	3	2
BRCA	IPPKP1 →	+0.108	+5.270	<.001	.001	3	2
READ	DPP3P1 →	+0.126	+4.070	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

MIR6803 by DAW1 expression — UCEC

Explore this box plot interactively →