DAW1

Across TCGA patient cohorts, DAW1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAW1-associated genes across cancer lineages are Annexin-1, ASNS, and ATM. Each is linked with DAW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAW1-to-partner and partner-to-DAW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by DAW1-low versus DAW1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAW1→partner) and Y-score (partner→DAW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.535	+2.584	.002	.010	3	2
UCEC	ASNS →	+0.383	+1.415	.001	.043	3	2
UCEC	ATM →	-0.544	-1.584	<.001	.009	3	2
UCEC	Beclin →	+0.067	+1.874	.034	.002	3	2
UCEC	4E-BP1_pT37_T46 →	-0.285	-1.687	.023	.040	3	2
UCEC	4E-BP1 →	+0.275	+2.115	.002	.016	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Annexin-1 by DAW1 expression — UCEC

Explore this box plot interactively →