DAW1

Across TCGA cell cohorts, DAW1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DAW1-associated genes across cancer lineages are ANKRD40CL, OR2T3, and KRTAP10-4. Each is linked with DAW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAW1-to-partner and partner-to-DAW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD40CL grouped by DAW1-low versus DAW1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAW1→partner) and Y-score (partner→DAW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ANKRD40CL →	+0.057	+3.793	<.001	.007	3	1
SKIN	OR2T3 →	+0.010	+4.437	<.001	.004	3	1
SKIN	KRTAP10-4 →	+0.012	+4.437	<.001	.004	3	1
BLOOD_Lymphoma	TPRX1 →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR5P2 →	+0.028	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ANKRD40CL by DAW1 expression — SKIN

Explore this box plot interactively →