DAPP1

Across TCGA cell cohorts, DAPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,571 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible DAPP1-associated GO terms across cancer lineages are IMP biosynthetic process, Positive regulation of iron ion transport, and Positive regulation of iron ion transmembrane transport. Each is linked with DAPP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DAPP1-to-partner and partner-to-DAPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by DAPP1-low versus DAPP1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPP1→partner) and Y-score (partner→DAPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	IMP biosynthetic process →	-0.178	-2.739	<.001	.001	3	12
URINARY_TRACT	Positive regulation of iron ion transport →	+1.740	+2.700	<.001	.001	3	12
URINARY_TRACT	Positive regulation of iron ion transmembrane transport →	+1.740	+2.700	<.001	.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of high-density lipoprotein particle clearance →	+1.559	+3.260	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of hippocampal neuron apoptotic process →	+1.926	+3.348	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of hippocampal neuron apoptotic process →	+1.810	+3.327	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,571 associations by consensus.

IMP biosynthetic process by DAPP1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →