DAPK3

Across TCGA patient cohorts, DAPK3 RNA expression is significantly associated with the mutation status of many other genes, with 10,633 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAPK3-associated genes across cancer lineages are NSD1, MUC2, and PTPRD. Each is linked with DAPK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both DAPK3-to-partner and partner-to-DAPK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NSD1 grouped by DAPK3-low versus DAPK3-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK3→partner) and Y-score (partner→DAPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	NSD1 →	+3.495	+0.393	.002	.004	3	4
SKCM	MUC2 →	+1.468	+0.329	<.001	<.001	3	4
UCEC	PTPRD →	+1.720	+0.396	<.001	<.001	3	4
UCEC	CHD3 →	+2.086	+0.446	<.001	<.001	3	4
SARC	TP53 →	+1.540	+0.309	<.001	.001	3	3
UCEC	EGFR →	+2.269	+0.498	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,633 associations by consensus.

NSD1 by DAPK3 expression — LUSC

Explore this box plot interactively →