DAPK3

Across TCGA cell cohorts, DAPK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,985 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DAPK3-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Negative regulation of Rho protein signal transduction, and Endocytic recycling. Each is linked with DAPK3 in more than 18 cancer types. Because this analysis shows association rather than direction, both DAPK3-to-partner and partner-to-DAPK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by DAPK3-low versus DAPK3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK3→partner) and Y-score (partner→DAPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.179	+0.650	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.167	+1.195	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Endocytic recycling →	+0.077	+0.942	<.001	.008	2	16
SOFT_TISSUE	Regulation of fibroblast proliferation →	+0.099	+0.837	<.001	.001	3	15
URINARY_TRACT	Protein depolymerization →	+0.130	+0.879	<.001	<.001	3	15
BONE	Actin filament depolymerization →	+0.236	+1.227	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,985 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by DAPK3 expression — LUNG_SCLC

Explore this box plot interactively →