DAPK2

Across TCGA pan-cancer cohorts, DAPK2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DAPK2 data layer compared with 30 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DAPK2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DAPK2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

UCEC, COAD, and PDAC are the cancer types where DAPK2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.902	.006	28	view →
COAD	DFS	Median	II,III,IV	1.000	0.916	.019	18	view →
PDAC	DFS	Tertile	III,IV	0.196	0.834	.024	6	view →
HNSC	OS	Median	II,III,IV	0.962	1.000	.035	4	view →
CCRCC	DFS	Median	All	0.544	0.913	.022	3	view →
LUAD	DFS	Tertile	All	0.929	0.638	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DAPK2–UCEC (OS)

Open the UCEC breakdown →