DAPK2

Across TCGA patient cohorts, DAPK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,336 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DAPK2-associated proteins across cancer lineages are DAPK2_S299, DAPK2_S349, and RPS6KA3. Each is linked with DAPK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DAPK2-to-partner and partner-to-DAPK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAPK2 versus DAPK2_S299 in PDAC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK2→partner) and Y-score (partner→DAPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DAPK2_S299 →	+0.584	+0.623	<.001	<.001	3	8
OV	DAPK2_S349 →	+0.984	+0.819	<.001	<.001	3	6
HNSC	RPS6KA3 →	+0.313	+0.716	<.001	<.001	3	5
LUAD	TRIM2 →	+0.626	+0.853	<.001	<.001	3	5
LUAD	DYNC1LI2_S194 →	-0.392	-0.702	<.001	<.001	3	4
PDAC	GNG12_S49 →	+0.581	+0.428	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,336 associations by consensus.

DAPK2 vs DAPK2_S299 — PDAC

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