DAPK2

Across TCGA patient cohorts, DAPK2 mutation is significantly associated with the RNA expression of many other genes, with 2,973 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAPK2-associated genes across cancer lineages are MRPL37, ATP1B2, and RNU1-62P. Each is linked with DAPK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAPK2-to-partner and partner-to-DAPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL37 grouped by DAPK2-low versus DAPK2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK2→partner) and Y-score (partner→DAPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL37 →	+0.529	+3.321	<.001	<.001	3	3
UCEC	ATP1B2 →	-0.718	-3.796	.003	<.001	3	3
CESC	RNU1-62P →	+0.192	+4.539	<.001	.008	3	2
CESC	HNRNPH1P2 →	+0.059	+5.060	<.001	.001	3	2
CESC	LINC01712 →	+0.043	+5.342	<.001	.002	3	2
UCEC	CRYBB2P1 →	+0.532	+3.063	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,973 associations by consensus.

MRPL37 by DAPK2 expression — UCEC

Explore this box plot interactively →