DAPK2

Across TCGA cell cohorts, DAPK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAPK2-associated GO terms across cancer lineages are Negative regulation of autophagy, Negative regulation of myoblast fusion, and Regulation of myoblast fusion. Each is linked with DAPK2 in more than 10 cancer types. Because this analysis shows association rather than direction, both DAPK2-to-partner and partner-to-DAPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by DAPK2-low versus DAPK2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK2→partner) and Y-score (partner→DAPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of autophagy →	+0.059	+0.994	<.001	<.001	3	11
OVARY	Negative regulation of myoblast fusion →	+0.086	+0.822	<.001	<.001	3	10
OVARY	Regulation of myoblast fusion →	+0.108	+0.871	<.001	.004	3	10
SKIN	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.097	+0.617	<.001	<.001	3	10
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.086	+0.795	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Positive regulation of autophagy →	+0.040	+0.778	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Negative regulation of autophagy by DAPK2 expression — CNS

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