DAPK1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DAPK1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DAPK1 data layer compared with 27 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DAPK1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DAPK1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where DAPK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIII,IV1.0000.494.01618view →
CCRCCOSMedianAll0.9580.829.01510view →
LUADOSTertileAll1.0000.937.0382view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration