Across TCGA patient cohorts, DAPK1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAPK1-associated genes across cancer lineages are eIF4E, ASNS, and PTEN. Each is linked with DAPK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAPK1-to-partner and partner-to-DAPK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK1→partner) and Y-score (partner→DAPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.205	+1.550	<.001	<.001	3	3
COAD	ASNS →	+0.375	+2.095	.006	.003	3	3
UCEC	PTEN →	-0.235	-0.807	.016	.042	3	3
UCEC	TFRC →	+0.310	+1.064	.018	.043	3	3
UCEC	Bak →	+0.130	+1.115	.035	.022	3	3
UCEC	c-Met_pY1235 →	+0.036	+0.903	.049	.042	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

DAPK1 survival (RNA) · tumor vs normal (RNA) · all DAPK1 data types