Across TCGA cell cohorts, DAPK1 mutation is significantly associated with the RNA expression of many other genes, with 901 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DAPK1-associated genes across cancer lineages are SPRR2G, USP17L4, and SEMA3G. Each is linked with DAPK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAPK1-to-partner and partner-to-DAPK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAPK1→partner) and Y-score (partner→DAPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SPRR2G →	+0.309	+3.515	.001	.003	3	2
SOFT_TISSUE	USP17L4 →	+0.014	+3.464	.006	.001	3	2
LARGE_INTESTINE	SEMA3G →	+0.733	+2.158	.001	.004	3	2
LARGE_INTESTINE	C1QBP →	+0.728	+2.244	<.001	.003	3	2
LARGE_INTESTINE	USP46 →	+0.714	+2.936	<.001	<.001	3	2
LARGE_INTESTINE	KLHL2 →	+0.608	+2.850	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 901 associations by consensus.

Exploration

DAPK1 survival (RNA) · tumor vs normal (RNA) · all DAPK1 data types