DAP

Across TCGA cell cohorts, DAP RNA expression is significantly associated with the RNA expression of many other genes, with 10,530 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible DAP-associated genes across cancer lineages are ZNF622, OTULIN, and GOLPH3. Each is linked with DAP in more than 14 cancer types. Because this analysis shows association rather than direction, both DAP-to-partner and partner-to-DAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAP versus ZNF622 in LIVER, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAP→partner) and Y-score (partner→DAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ZNF622 →	+1.417	+1.531	<.001	<.001	3	15
LUNG_SCLC	OTULIN →	+0.961	+1.235	<.001	<.001	3	14
URINARY_TRACT	GOLPH3 →	+1.105	+1.775	<.001	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	RAD1 →	+1.002	+1.213	<.001	<.001	3	13
LIVER	MED10 →	+1.160	+1.267	.002	<.001	2	14
UPPER_AERODIGESTIVE_TRACT	DNAJC21 →	+0.896	+1.231	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,530 associations by consensus.

DAP vs ZNF622 — LIVER

Explore this scatter interactively →