DAP

Across TCGA cell cohorts, DAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,640 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DAP-associated GO terms across cancer lineages are Ribosome hibernation, Cellular response to rapamycin, and Response to rapamycin. Each is linked with DAP in more than 17 cancer types. Because this analysis shows association rather than direction, both DAP-to-partner and partner-to-DAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome hibernation grouped by DAP-low versus DAP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAP→partner) and Y-score (partner→DAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ribosome hibernation →	+0.180	+1.157	<.001	<.001	3	18
LIVER	Cellular response to rapamycin →	+0.182	+1.068	.005	.005	3	12
LIVER	Response to rapamycin →	+0.173	+1.213	.008	.005	3	12
KIDNEY	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.088	+0.914	<.001	<.001	3	11
BONE	Small GTPase-mediated signal transduction →	+0.049	+1.011	<.001	<.001	3	11
SOFT_TISSUE	Rho protein signal transduction →	+0.105	+1.384	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,640 associations by consensus.

Ribosome hibernation by DAP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →