DAOA

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DAOA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,287 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DAOA-associated GO terms across cancer lineages are NADH dehydrogenase complex assembly, Release of cytochrome c from mitochondria, and Regulation of cytokinesis. Each is linked with DAOA in more than 7 cancer types. Because this analysis shows association rather than direction, both DAOA-to-partner and partner-to-DAOA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADH dehydrogenase complex assembly grouped by DAOA-low versus DAOA-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAOA→partner) and Y-score (partner→DAOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNADH dehydrogenase complex assembly →+0.086+0.102<.001<.00138
STADRelease of cytochrome c from mitochondria →+0.075+0.097<.001<.00138
STADRegulation of cytokinesis →+0.074+0.097<.001<.00138
STADRegulation of polysaccharide biosynthetic process →+0.068+0.084<.001<.00138
STADRegulation of microtubule-based process →+0.064+0.109<.001<.00138
STADRegulation of chromosome organization →+0.089+0.099<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,287 associations by consensus.

NADH dehydrogenase complex assembly by DAOA expression — STAD

Box plot of NADH dehydrogenase complex assembly in DAOA-low vs DAOA-high samples in STAD.

Explore this box plot interactively →

Exploration