DAOA

Across TCGA cell cohorts, DAOA RNA expression is significantly associated with the mutation status of many other genes, with 98 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DAOA-associated genes across cancer lineages are FAT1, MYRF, and EPHA7. Each is linked with DAOA in more than 1 cancer types. Because this analysis shows association rather than direction, both DAOA-to-partner and partner-to-DAOA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAT1 grouped by DAOA-low versus DAOA-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAOA→partner) and Y-score (partner→DAOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FAT1 →	+2.722	+0.016	.007	<.001	3	2
LUNG_NSCLC_LUAD	MYRF →	+3.944	+0.010	.006	<.001	3	2
LUNG_NSCLC_LUAD	EPHA7 →	+3.681	+0.008	.009	<.001	3	2
LUNG_NSCLC_LUAD	CCDC39 →	+5.266	+0.017	.001	<.001	3	2
LUNG_NSCLC_LUAD	SLC15A2 →	+4.681	+0.014	.003	<.001	3	2
BLOOD_Leukemia	TANC1 →	+2.954	+0.014	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

FAT1 by DAOA expression — URINARY_TRACT

Explore this box plot interactively →