DAO

Across TCGA patient cohorts, DAO RNA expression is significantly associated with the go_rna of many other GO terms, with 7,113 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DAO-associated GO terms across cancer lineages are Reactive nitrogen species metabolic process, Stress-activated protein kinase signaling cascade, and Positive regulation of JNK cascade. Each is linked with DAO in more than 16 cancer types. Because this analysis shows association rather than direction, both DAO-to-partner and partner-to-DAO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reactive nitrogen species metabolic process grouped by DAO-low versus DAO-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAO→partner) and Y-score (partner→DAO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Reactive nitrogen species metabolic process →	+0.057	+0.189	<.001	<.001	3	17
STAD	Stress-activated protein kinase signaling cascade →	+0.061	+0.180	<.001	<.001	3	16
STAD	Positive regulation of JNK cascade →	+0.056	+0.181	<.001	<.001	3	15
STAD	Regulation of cell shape →	+0.068	+0.201	<.001	<.001	3	15
STAD	Tissue homeostasis →	+0.048	+0.177	<.001	<.001	3	15
STAD	Regulation of cell morphogenesis →	+0.061	+0.177	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,113 associations by consensus.

Reactive nitrogen species metabolic process by DAO expression — STAD

Explore this box plot interactively →