DAO

Across TCGA patient cohorts, DAO protein abundance is significantly associated with the RNA expression of many other genes, with 5,405 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DAO-associated genes across cancer lineages are MT4, LRP3, and PLXNC1. Each is linked with DAO in more than 1 cancer types. Because this analysis shows association rather than direction, both DAO-to-partner and partner-to-DAO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAO versus MT4 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAO→partner) and Y-score (partner→DAO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MT4 →	+0.316	+1.972	<.001	<.001	3	1
GBM	LRP3 →	-1.146	-1.258	<.001	.007	3	1
GBM	PLXNC1 →	+1.064	+1.529	<.001	.007	3	1
GBM	DUOXA2 →	+0.213	+1.487	.001	.008	3	1
GBM	ALCAM →	+1.381	+0.719	.001	.006	3	1
GBM	LINC00469 →	+0.055	+1.402	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,405 associations by consensus.

DAO vs MT4 — GBM

Explore this scatter interactively →