DALRD3

Across TCGA patient cohorts, DALRD3 mutation is significantly associated with the RNA expression of many other genes, with 226 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DALRD3-associated genes across cancer lineages are RNU6-91P, RRM2P4, and M6PRP1. Each is linked with DALRD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DALRD3-to-partner and partner-to-DALRD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-91P grouped by DALRD3-low versus DALRD3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DALRD3→partner) and Y-score (partner→DALRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-91P →	+0.285	+3.816	.001	.007	3	2
SKCM	RRM2P4 →	+0.033	+4.302	<.001	.007	3	2
BRCA	M6PRP1 →	+0.023	+4.464	<.001	.005	3	2
UCEC	RNA5SP419 →	+1.366	+3.077	<.001	.005	3	2
LIHC	MIR766 →	+0.413	+4.240	.001	.008	3	2
LUSC	RNU6-61P →	+0.216	+5.148	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 226 associations by consensus.

RNU6-91P by DALRD3 expression — CESC

Explore this box plot interactively →