DAGLB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DAGLB protein abundance is significantly associated with the RNA expression of many other genes, with 11,183 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DAGLB-associated genes across cancer lineages are C1GALT1, RAC1, and KDELR2. Each is linked with DAGLB in more than 3 cancer types. Because this analysis shows association rather than direction, both DAGLB-to-partner and partner-to-DAGLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAGLB versus C1GALT1 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAGLB→partner) and Y-score (partner→DAGLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVC1GALT1 →+0.637+0.301<.001<.00134
HNSCRAC1 →+0.647+0.376<.001<.00124
HNSCKDELR2 →+0.606+0.354<.001<.00124
OVMIOS →+0.500+0.318<.001<.00133
OVBIRC3 →+1.138+0.213<.001.00233
GBMTREM1 →+1.104+0.169.001.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,183 associations by consensus.

DAGLB vs C1GALT1 — OV

Per-sample scatter of DAGLB vs C1GALT1 in OV (Pearson r = 0.38).

Explore this scatter interactively →

Exploration