DAGLB

Across TCGA patient cohorts, DAGLB mutation is significantly associated with the RNA expression of many other genes, with 1,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAGLB-associated genes across cancer lineages are LINC02517, RN7SL810P, and YPEL5P1. Each is linked with DAGLB in more than 2 cancer types. Because this analysis shows association rather than direction, both DAGLB-to-partner and partner-to-DAGLB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02517 grouped by DAGLB-low versus DAGLB-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAGLB→partner) and Y-score (partner→DAGLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02517 →	+0.056	+6.164	<.001	<.001	3	3
CESC	RN7SL810P →	+0.179	+4.874	.002	.002	3	2
CESC	YPEL5P1 →	+0.111	+5.345	.006	.001	3	2
UCEC	PLAAT1 →	-1.022	-3.237	<.001	<.001	3	2
UCEC	MDH1B →	-0.690	-2.129	<.001	<.001	3	2
UCEC	SNHG28 →	-0.530	-3.226	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,745 associations by consensus.

LINC02517 by DAGLB expression — CESC

Explore this box plot interactively →