DAGLA

Across TCGA pan-cancer cohorts, DAGLA RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DAGLA’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where DAGLA RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DAGLA is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

LIHC, HNSC, and KICH are the cancer types where DAGLA tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DAGLA RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.407	<.001	8	view →
HNSC	Male	All	−0.785	<.001	8	view →
KICH	Male	All	−1.858	<.001	7	view →
LUSC	All	II,III,IV	−0.716	<.001	6	view →
BLCA	Female	All	+0.960	.009	5	view →
STAD	All	All	+0.944	<.001	4	view →
BRCA	Female	II,III,IV	−0.370	.001	4	view →
CHOL	All	All	+1.858	<.001	3	view →
THCA	All	All	+0.365	<.001	3	view →
COAD	All	All	+0.341	.017	2	view →
KIRC	Male	All	−0.298	.021	2	view →
READ	Female	All	+0.617	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DAGLA–LIHC

Open the LIHC breakdown →