DAG1

Across TCGA patient cohorts, DAG1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,883 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DAG1-associated genes across cancer lineages are CDO1, SCN7A, and GASK1A. Each is linked with DAG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DAG1-to-partner and partner-to-DAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAG1 versus CDO1 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAG1→partner) and Y-score (partner→DAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDO1 →	+1.311	+0.571	<.001	<.001	3	6
PDAC	SCN7A →	+1.224	+0.280	<.001	<.001	3	6
BRCA	GASK1A →	+0.955	+0.240	<.001	<.001	3	6
CCRCC	CLEC14A →	+0.975	+0.209	<.001	<.001	3	6
UCEC	EPHA3 →	+1.038	+0.178	.003	.005	3	6
BRCA	SORBS1 →	+1.076	+0.214	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,883 associations by consensus.

DAG1 vs CDO1 — HNSC

Explore this scatter interactively →