DAG1

Across TCGA cell cohorts, DAG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,710 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DAG1-associated GO terms across cancer lineages are Nerve maturation, Endosomal transport, and Regulation of early endosome to late endosome transport. Each is linked with DAG1 in more than 14 cancer types. Because this analysis shows association rather than direction, both DAG1-to-partner and partner-to-DAG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nerve maturation grouped by DAG1-low versus DAG1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAG1→partner) and Y-score (partner→DAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Nerve maturation →	+0.987	+0.689	<.001	.003	3	15
BONE	Endosomal transport →	+0.061	+0.643	.001	.002	3	12
BREAST	Regulation of early endosome to late endosome transport →	+0.116	+1.320	<.001	<.001	3	12
STOMACH	Phospholipid biosynthetic process →	+0.058	+1.482	<.001	.003	3	12
STOMACH	Postsynapse to nucleus signaling pathway →	+0.174	+1.462	<.001	.002	3	12
LIVER	Vacuole organization →	+0.056	+1.113	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,710 associations by consensus.

Nerve maturation by DAG1 expression — BLOOD_Leukemia

Explore this box plot interactively →