DAD1

Across TCGA patient cohorts, DAD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,703 significant associations in total. OV shows the largest number of these associations.

The most reproducible DAD1-associated genes across cancer lineages are VIP, PLEKHG3, and DCTN1. Each is linked with DAD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DAD1-to-partner and partner-to-DAD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAD1 versus VIP in GBM, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAD1→partner) and Y-score (partner→DAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VIP →	-0.468	-0.500	<.001	<.001	3	5
CCRCC	PLEKHG3 →	-0.712	-0.462	<.001	<.001	3	5
OV	DCTN1 →	-0.842	-0.301	<.001	<.001	3	5
LSCC	EXOC6B →	-0.733	-0.385	<.001	<.001	3	5
OV	WDR59 →	-0.487	-0.235	.001	.005	3	4
HNSC	STN1 →	-0.452	-0.325	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,703 associations by consensus.

DAD1 vs VIP — GBM

Explore this scatter interactively →