Across TCGA patient cohorts, DACT3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DACT3-associated genes across cancer lineages are Mesangial cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with DACT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DACT3-to-partner and partner-to-DACT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DACT3→partner) and Y-score (partner→DACT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.061	-2.989	.006	.037	3	1
UCEC	Endothelial cells →	-0.043	-2.957	.048	.037	1	1
UCEC	lymphatic Endothelial cells →	-0.028	-2.946	.042	.037	1	1
UCEC	mv Endothelial cells →	-0.028	-2.989	.040	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

DACT3 survival (RNA) · tumor vs normal (RNA) · all DACT3 data types