DACT2

Across TCGA patient cohorts, DACT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,731 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DACT2-associated proteins across cancer lineages are PLIN3, PPP1R13L, and MAP1B_S1154. Each is linked with DACT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DACT2-to-partner and partner-to-DACT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DACT2 versus PLIN3 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DACT2→partner) and Y-score (partner→DACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLIN3 →	-0.490	-0.964	<.001	<.001	3	4
LSCC	PPP1R13L →	-0.394	-1.208	<.001	<.001	3	4
LSCC	MAP1B_S1154 →	+1.088	+1.948	<.001	<.001	3	4
OV	ARFGEF2 →	-0.329	-1.351	<.001	<.001	3	4
COAD	SH3BP4 →	+0.295	+0.594	<.001	.001	3	4
HNSC	STRBP →	+0.519	+1.206	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,731 associations by consensus.

DACT2 vs PLIN3 — GBM

Explore this scatter interactively →