DACT2

Across TCGA patient cohorts, DACT2 protein abundance is significantly associated with the protein abundance of many other proteins, with 448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DACT2-associated proteins across cancer lineages are ARHGDIA_S47, RPL36AL, and RPS6KA4_T22. Each is linked with DACT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DACT2-to-partner and partner-to-DACT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DACT2 versus ARHGDIA_S47 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DACT2→partner) and Y-score (partner→DACT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARHGDIA_S47 →	+0.832	+1.012	<.001	.003	3	1
UCEC	RPL36AL →	+0.541	+0.679	.004	.003	3	1
UCEC	RPS6KA4_T22 →	-0.898	-0.948	.001	<.001	3	1
UCEC	SHROOM4_S459 →	-0.366	-0.917	<.001	.001	3	1
UCEC	SIAE →	+0.726	+0.807	.001	<.001	3	1
UCEC	SLC12A2_S940 →	+2.479	+1.363	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 448 associations by consensus.

DACT2 vs ARHGDIA_S47 — UCEC

Explore this scatter interactively →