DACT1

Across TCGA patient cohorts, DACT1 protein abundance is significantly associated with the protein abundance of many other proteins, with 382 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DACT1-associated proteins across cancer lineages are BCAS2, C11orf52, and C1QTNF3. Each is linked with DACT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DACT1-to-partner and partner-to-DACT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DACT1 versus BCAS2 in BRCA, with a Pearson correlation of -0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DACT1→partner) and Y-score (partner→DACT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BCAS2 →	-0.252	-0.730	<.001	.006	3	1
BRCA	C11orf52 →	+1.691	+1.003	.001	<.001	3	1
BRCA	C1QTNF3 →	+1.619	+1.032	<.001	<.001	3	1
BRCA	CEP295_S14 →	-0.398	-0.746	.001	.007	3	1
BRCA	COL1A1_S291 →	+1.597	+1.145	.001	<.001	3	1
BRCA	COL2A1 →	+1.215	+1.120	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 382 associations by consensus.

DACT1 vs BCAS2 — BRCA

Explore this scatter interactively →