DAB2IP

Across TCGA pan-cancer cohorts, DAB2IP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DAB2IP data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DAB2IP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DAB2IP expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and LSCC are the cancer types where DAB2IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.915	0.795	.005	23	view →
HNSC	DFS	Tertile	All	0.857	0.658	.021	13	view →
LSCC	OS	Quartile	II,III,IV	0.572	0.903	.011	13	view →
UCEC	DFS	Tertile	All	0.958	0.805	.014	10	view →
LUAD	OS	Median	All	0.988	0.933	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DAB2IP–PDAC (OS)

Open the PDAC breakdown →