DAB2IP

Across TCGA patient cohorts, DAB2IP mutation is significantly associated with the RNA expression of many other genes, with 4,910 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAB2IP-associated genes across cancer lineages are RPL26L1, SKA2, and CEP57L1. Each is linked with DAB2IP in more than 3 cancer types. Because this analysis shows association rather than direction, both DAB2IP-to-partner and partner-to-DAB2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL26L1 grouped by DAB2IP-low versus DAB2IP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2IP→partner) and Y-score (partner→DAB2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL26L1 →	+0.728	+3.732	<.001	<.001	3	4
UCEC	SKA2 →	+0.505	+1.680	<.001	<.001	3	4
UCEC	CEP57L1 →	+0.320	+2.501	<.001	<.001	3	4
UCEC	TEX30 →	+0.468	+1.651	<.001	.001	3	3
UCEC	HAUS1 →	+0.446	+2.413	<.001	<.001	3	3
UCEC	SAR1B →	+0.512	+2.478	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,910 associations by consensus.

RPL26L1 by DAB2IP expression — SKCM

Explore this box plot interactively →