DAB2IP

Across TCGA cell cohorts, DAB2IP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,166 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAB2IP-associated GO terms across cancer lineages are Positive regulation of IRE1-mediated unfolded protein response, Negative regulation of G0 to G1 transition, and Positive regulation of synapse maturation. Each is linked with DAB2IP in more than 14 cancer types. Because this analysis shows association rather than direction, both DAB2IP-to-partner and partner-to-DAB2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of IRE1-mediated unfolded protein response grouped by DAB2IP-low versus DAB2IP-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2IP→partner) and Y-score (partner→DAB2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of IRE1-mediated unfolded protein response →	+0.184	+1.726	<.001	<.001	2	15
SOFT_TISSUE	Negative regulation of G0 to G1 transition →	+0.318	+1.213	.004	<.001	3	14
BONE	Positive regulation of synapse maturation →	+0.290	+1.157	<.001	<.001	3	14
LIVER	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.137	+2.250	<.001	.001	3	14
LARGE_INTESTINE	Negative regulation of protein-containing complex assembly →	+0.072	+1.594	<.001	<.001	3	13
LUNG_SCLC	Endothelial cell apoptotic process →	+0.402	+1.573	.005	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,166 associations by consensus.

Positive regulation of IRE1-mediated unfolded protein response by DAB2IP expression — URINARY_TRACT

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