DAB2IP

Across TCGA cell cohorts, DAB2IP mutation is significantly associated with the RNA expression of many other genes, with 674 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DAB2IP-associated genes across cancer lineages are PRR30, GOLGA6L1, and TMEM52. Each is linked with DAB2IP in more than 1 cancer types. Because this analysis shows association rather than direction, both DAB2IP-to-partner and partner-to-DAB2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR30 grouped by DAB2IP-low versus DAB2IP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAB2IP→partner) and Y-score (partner→DAB2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRR30 →	+0.017	+3.684	<.001	.004	3	2
BLOOD_Leukemia	GOLGA6L1 →	+0.026	+3.475	<.001	.006	3	2
LARGE_INTESTINE	TMEM52 →	+1.257	+3.459	<.001	<.001	3	2
STOMACH	APOL5 →	+0.011	+3.209	<.001	.007	3	1
STOMACH	HBG1 →	+0.176	+3.700	.004	.003	3	1
STOMACH	USP17L3 →	+0.004	+3.209	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 674 associations by consensus.

PRR30 by DAB2IP expression — BLOOD_Leukemia

Explore this box plot interactively →