DAAM2

Across TCGA cell cohorts, DAAM2 mutation is significantly associated with the RNA expression of many other genes, with 950 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DAAM2-associated genes across cancer lineages are ADPRM, GRSF1, and CENPS. Each is linked with DAAM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DAAM2-to-partner and partner-to-DAAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADPRM grouped by DAAM2-low versus DAAM2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAAM2→partner) and Y-score (partner→DAAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADPRM →	+0.590	+2.548	.003	.006	3	3
BLOOD_Leukemia	GRSF1 →	+0.516	+3.366	<.001	.002	3	3
BLOOD_Leukemia	CENPS →	+0.496	+3.321	<.001	.005	3	3
LARGE_INTESTINE	R3HCC1 →	+0.661	+3.502	.008	.001	3	2
LARGE_INTESTINE	RAD51C →	+0.847	+2.451	.003	.009	3	2
LARGE_INTESTINE	DPH5 →	+0.569	+3.502	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 950 associations by consensus.

ADPRM by DAAM2 expression — BLOOD_Leukemia

Explore this box plot interactively →