DAAM2-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, DAAM2-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of DAAM2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DAAM2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DAAM2-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

KIRC, THCA, and BRCA are the cancer types where DAAM2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DAAM2-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCAllIII,IV+0.546<.00110view →
THCAAllAll−0.297<.0017view →
BRCAFemaleII,III,IV−0.826<.0016view →
LUSCAllII,III,IV−0.396<.0016view →
LUADAllIII,IV−0.361.0046view →
KIRPMaleII,III,IV−0.215<.0016view →
KICHAllAll−0.162.0015view →
UCECAllAll+0.664.0022view →
PRADAllAll−0.124.0212view →
COADAllAll−0.064.0382view →
BLCAFemaleIV+0.276.0421view →
LIHCMaleAll+0.112.0351view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

DAAM2-AS1–KIRC

Tumor-vs-normal expression box plot for DAAM2-AS1 RNA in KIRC.

Open the KIRC breakdown →

Exploration