DAAM1

Across TCGA pan-cancer cohorts, DAAM1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DAAM1 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher DAAM1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DAAM1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

OV, PRAD, and BLCA are the cancer types where DAAM1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.082	0.844	<.001	36	view →
PRAD	DFS	Median	All	0.617	0.886	.011	6	view →
BLCA	OS	Median	All	0.163	0.455	.043	4	view →
SKCM	DFS	Median	IV	1.000	0.201	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DAAM1–OV (OS)

Open the OV breakdown →