DAAM1

Across TCGA pan-cancer cohorts, DAAM1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DAAM1 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DAAM1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DAAM1 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, LUAD, and HNSC are the cancer types where DAAM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.916	.017	48	view →
LUAD	DFS	Tertile	All	0.578	0.836	.002	33	view →
HNSC	DFS	Median	All	1.000	0.907	.001	25	view →
UCEC	DFS	Quartile	II,III,IV	1.000	0.446	.018	12	view →
LSCC	DFS	Quartile	II,III,IV	0.841	0.433	.006	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DAAM1–COAD (DFS)

Open the COAD breakdown →