DAAM1

Across TCGA patient cohorts, DAAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,626 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DAAM1-associated genes across cancer lineages are SLAMF1, CIITA, and ATP6V1D. Each is linked with DAAM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DAAM1-to-partner and partner-to-DAAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DAAM1 versus SLAMF1 in HNSC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAAM1→partner) and Y-score (partner→DAAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLAMF1 →	-0.731	-0.330	<.001	.001	3	5
HNSC	CIITA →	-0.826	-0.355	<.001	<.001	3	4
HNSC	ATP6V1D →	+0.590	+0.442	<.001	<.001	3	4
HNSC	VTI1B →	+0.422	+0.233	.006	.005	3	4
LSCC	HSPA2 →	+1.363	+0.437	<.001	<.001	3	4
UCEC	APOL3 →	-1.035	-0.622	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,626 associations by consensus.

DAAM1 vs SLAMF1 — HNSC

Explore this scatter interactively →