DAAM1

Across TCGA patient cohorts, DAAM1 mutation is significantly associated with the RNA expression of many other genes, with 5,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DAAM1-associated genes across cancer lineages are EIF3JP1, RAD17, and OXNAD1. Each is linked with DAAM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DAAM1-to-partner and partner-to-DAAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF3JP1 grouped by DAAM1-low versus DAAM1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAAM1→partner) and Y-score (partner→DAAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF3JP1 →	+0.327	+4.875	<.001	.002	3	3
UCEC	RAD17 →	+0.376	+2.269	<.001	<.001	3	3
BLCA	OXNAD1 →	+0.477	+3.205	.003	.009	3	3
UCEC	ATP5MC1 →	+0.354	+1.954	.001	<.001	3	3
UCEC	DFFA →	+0.472	+1.790	<.001	<.001	3	3
UCEC	CPSF4 →	+0.337	+3.119	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,564 associations by consensus.

EIF3JP1 by DAAM1 expression — BRCA

Explore this box plot interactively →