DAAM1

Across TCGA cell cohorts, DAAM1 mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DAAM1-associated genes across cancer lineages are GHRHR, MAGEB4, and PAGE4. Each is linked with DAAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DAAM1-to-partner and partner-to-DAAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by DAAM1-low versus DAAM1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DAAM1→partner) and Y-score (partner→DAAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GHRHR →	+0.451	+4.705	<.001	.003	3	2
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.192	<.001	.002	3	2
BLOOD_Lymphoma	PAGE4 →	+1.640	+3.554	<.001	.007	3	2
BLOOD_Lymphoma	SGCZ →	+0.403	+3.762	.003	.004	3	2
BLOOD_Lymphoma	CT45A1 →	+2.799	+3.523	<.001	.008	3	2
BLOOD_Lymphoma	CT45A2 →	+1.404	+4.165	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

GHRHR by DAAM1 expression — BLOOD_Leukemia

Explore this box plot interactively →