CZIB

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CZIB RNA expression is significantly associated with the protein abundance of many other proteins, with 18,356 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CZIB-associated proteins across cancer lineages are NFIA, MRPS10, and MRPS15. Each is linked with CZIB in more than 5 cancer types. Because this analysis shows association rather than direction, both CZIB-to-partner and partner-to-CZIB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CZIB versus NFIA in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CZIB→partner) and Y-score (partner→CZIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNFIA →+0.423+0.315<.001<.00136
COADMRPS10 →-0.449-0.413<.001<.00135
COADMRPS15 →-0.403-0.395<.001<.00135
COADMRPS5 →-0.359-0.417<.001<.00135
GBMMZB1 →-0.857-0.366<.001<.00135
BRCAUBE2J1 →-0.506-0.332<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,356 associations by consensus.

CZIB vs NFIA — GBM

Per-sample scatter of CZIB vs NFIA in GBM (Pearson r = 0.53).

Explore this scatter interactively →

Exploration