CYTL1

Across TCGA cell cohorts, CYTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,782 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYTL1-associated GO terms across cancer lineages are Regulation of translational initiation, Regulation of syncytium formation by plasma membrane fusion, and Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Each is linked with CYTL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYTL1-to-partner and partner-to-CYTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by CYTL1-low versus CYTL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTL1→partner) and Y-score (partner→CYTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of translational initiation →	+0.078	+0.126	<.001	.009	3	8
SOFT_TISSUE	Regulation of syncytium formation by plasma membrane fusion →	+0.053	+1.835	<.001	<.001	3	7
SOFT_TISSUE	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.063	+2.260	.001	.006	3	7
BONE	Mitochondrial electron transport, NADH to ubiquinone →	+0.092	+2.040	<.001	.005	3	7
SKIN	Endosomal transport →	+0.043	+2.681	.005	.008	3	6
OVARY	Ribonucleotide biosynthetic process →	+0.063	+1.856	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,782 associations by consensus.

Regulation of translational initiation by CYTL1 expression — OESOPHAGUS

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