CYTH4

Across TCGA patient cohorts, CYTH4 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,961 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYTH4-associated proteins across cancer lineages are ARHGEF6_S225, PTPN6, and PTPN7. Each is linked with CYTH4 in more than 9 cancer types. Because this analysis shows association rather than direction, both CYTH4-to-partner and partner-to-CYTH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYTH4 versus ARHGEF6_S225 in LSCC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTH4→partner) and Y-score (partner→CYTH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF6_S225 →	+0.879	+0.916	<.001	<.001	3	10
GBM	PTPN6 →	+0.789	+1.171	<.001	<.001	3	10
LSCC	PTPN7 →	+0.565	+0.902	<.001	<.001	3	10
GBM	PTPRC →	+0.923	+1.298	<.001	<.001	3	10
GBM	VSIG4 →	+0.987	+1.106	<.001	<.001	3	10
GBM	WAS →	+0.812	+1.267	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,961 associations by consensus.

CYTH4 vs ARHGEF6_S225 — LSCC

Explore this scatter interactively →