CYTH4

Across TCGA patient cohorts, CYTH4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,881 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYTH4-associated genes across cancer lineages are NCF4, LILRB1, and CD33. Each is linked with CYTH4 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYTH4-to-partner and partner-to-CYTH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYTH4 versus NCF4 in GBM, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTH4→partner) and Y-score (partner→CYTH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCF4 →	+1.243	+0.647	<.001	<.001	3	8
GBM	LILRB1 →	+1.069	+0.634	<.001	<.001	3	8
GBM	CD33 →	+0.912	+0.677	<.001	<.001	3	8
GBM	CD4 →	+1.211	+0.613	<.001	<.001	3	8
GBM	BTK →	+1.003	+0.683	<.001	<.001	3	8
GBM	IL10RA →	+1.299	+0.629	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,881 associations by consensus.

CYTH4 vs NCF4 — GBM

Explore this scatter interactively →