CYTH4

Across TCGA cell cohorts, CYTH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYTH4-associated GO terms across cancer lineages are Urokinase plasminogen activator signaling pathway, Regulation of cell-matrix adhesion, and Regulation of protein localization to mitochondrion. Each is linked with CYTH4 in more than 10 cancer types. Because this analysis shows association rather than direction, both CYTH4-to-partner and partner-to-CYTH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urokinase plasminogen activator signaling pathway grouped by CYTH4-low versus CYTH4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTH4→partner) and Y-score (partner→CYTH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Urokinase plasminogen activator signaling pathway →	+0.819	+0.552	.006	.009	3	11
LUNG_NSCLC_LUSC	Regulation of cell-matrix adhesion →	+0.075	+0.811	.002	.008	3	10
SOFT_TISSUE	Regulation of protein localization to mitochondrion →	+0.068	+0.389	<.001	.001	3	10
LIVER	Positive regulation of focal adhesion assembly →	+0.123	+0.939	<.001	.001	3	10
SOFT_TISSUE	Vesicle-mediated transport to the plasma membrane →	+0.062	+0.690	<.001	<.001	3	9
SOFT_TISSUE	Positive regulation of interleukin-8 production →	+0.099	+0.544	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,139 associations by consensus.

Urokinase plasminogen activator signaling pathway by CYTH4 expression — SOFT_TISSUE

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