CYTH1

Across TCGA cell cohorts, CYTH1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CYTH1-associated genes across cancer lineages are OR4D11, C12orf40, and KRTAP19-4. Each is linked with CYTH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYTH1-to-partner and partner-to-CYTH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D11 grouped by CYTH1-low versus CYTH1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYTH1→partner) and Y-score (partner→CYTH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4D11 →	+0.011	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	C12orf40 →	+0.184	+4.188	<.001	.001	3	1
LUNG_NSCLC_LUAD	KRTAP19-4 →	+0.141	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR4D11 by CYTH1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →