CYSTM1

Across TCGA patient cohorts, CYSTM1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,853 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYSTM1-associated genes across cancer lineages are C4BPB, NCOA3, and MEX3A. Each is linked with CYSTM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYSTM1-to-partner and partner-to-CYSTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYSTM1 versus C4BPB in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYSTM1→partner) and Y-score (partner→CYSTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C4BPB →	+1.145	+0.374	<.001	<.001	3	4
COAD	NCOA3 →	-0.441	-0.331	.002	.004	3	4
GBM	MEX3A →	-1.343	-0.461	<.001	<.001	3	4
OV	KIF3C →	-0.568	-0.313	.007	.002	3	4
COAD	TTI1 →	-0.678	-0.397	.003	.005	3	3
GBM	JADE3 →	-0.759	-0.420	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,853 associations by consensus.

CYSTM1 vs C4BPB — COAD

Explore this scatter interactively →